Estrogens have antioxidant properties which are due to their ability to bind
Estradiol as an antioxidant: incompati-ble with its physiological concentrations and
Introduction
This review describes the physiological and pathophysiological
The pathophysiology of neurodegeneration in the central nervous system is complex and multifactorial in nature and yet to be fully understood
The mechanisms through which estrogen promotes female-specific diseases The progressive loss of estrogen and its protective effects, combined with deficient endogenous antioxidant results in oxidative stress
The treatment with 17β-estradiol also reduced inflammatory mediators (Tnf
The antioxidant potency of 17β-estradiol and related polycyclic phenols has been well established
These mice were implanted with placebo or 17beta-estradiol pellets acutely or chronically
Methods: Thirty female Sprague-Dawley rats were randomly divided into three groups (sham, ovariectomized with vehicle, and
Taken together, our data suggest that AFP, a serum glycoprotein produced at high levels during fetal development, is a novel marker protein for the antioxidant effect of the placenta that exhibits synergistic antioxidant activity Estrogen deficiency in ovariectomized mice induced a downregulation of ecSOD and MnSOD expression, which was associated with increased production of vascular free radicals and prevented by estrogen replacement or treatment with PEG-SOD
The rate of decay of fluorescence in the presence of a 200 nM of 17 beta-estradiol, 17 alpha-estradiol and estriol expressed as percentages of the rate of decay in the absence of these compounds (control curve), were 74
2 +/- 2
005
005
Synthetic estrogens such as bisphenol A (BPA) and nonyl phenol (NP) are the
Amidst the concerning findings related to VAT and cognitive aging in women, the role of estradiol emerges as a potential protective factor
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