Jeffrey Juchau answered
Applies to: Tylenol with Codeine #3 (acetaminophen / codeine) and Cymbalta (duloxetine)
Either increases toxicity of the other by added drug
Drug Interactions between acetaminophen / tramadol and duloxetine
Very bad and sometimes deadly liver problems have happened with this medicine (duloxetine capsules)
Who can and cannot take it
Comments: An increase to 60 mg orally once a day may be considered after 2 weeks with an initial dose
The recommended dose of Cymbalta for treating depression is 20 or 30 mg twice daily or 60 mg once daily
15 Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of
It is only available on prescription
These side effects are usually mild and go away after a couple of Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor Using HYDROcodone together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or Common side effects may include: drowsiness; nausea, constipation, loss of appetite; dry mouth; or
The interaction may be more likely if you are elderly or have kidney or liver disease
If coadministered with strong or moderate CYP2D6 inhibitors, reduce eliglustat dose from 84 mg BID to 84 mg once daily in extensive and intermediate metabolizers; eliglustat is contraindiated if strong or moderate CYP2D6
- SNRIs
The recommended dosage in adults is 40 to 60 mg daily, which can be raised to 120 mg daily based upon tolerance and clinical effects
Like all medicines, duloxetine can cause side effects in some people
Capsules
There are 346 drugs known to interact with ondansetron, along with 2 disease interactions